GEN2PHEN
From IEETA
| Title | GEN2PHEN - Genotype-To-Phenotype Databases: A Holistic Solution |
|---|---|
| Reference | HEALTH theme - contract no. 200754 |
| PI | José Luís Oliveira |
| Participants | Silvina Santana, Carlos Costa, António J. S. Teixeira, Pedro Lopes, Joel Arrais, Ricardo Dias |
| Funded by | EU FP7 |
| Global funding (€) | |
| RU funding (€) | 335,048€462,366.24 USD |
| Starts | 2008/01/01 |
| Ends | 2013/12/31 |
Project Summary and Objectives
The GEN2PHEN project aims to unify human and model organism genetic variation databases towards increasingly holistic views into Genotype-To-Phenotype (G2P) data, and to link this system into other biomedical knowledge sources via genome browser functionality. The project will establish the technological building-blocks needed for the evolution of today’s diverse G2P databases into a future seamless G2P biomedical knowledge environment, by the projects end. This will consist of a European-centred but globally-networked hierarchy of bioinformatics GRID-linked databases, tools and standards, all tied into the Ensembl genome browser. The project has the following specific objectives:
- To analyse the G2P field and thus determine emerging needs and practices
- To develop key standards for the G2P database field
- To create generic database components, services and integration infrastructures for the G2P database domain
- To create search modalities and data presentation solutions for G2P knowledge
- To facilitate the process of populating G2P databases
- To build a major G2P internet portal
- To deploy GEN2PHEN solutions to the community
- To address system durability and long-term financing
- To undertake a whole-system utility and validation pilot study